The Center for Research on Mediation is a group of scholars of technology in the Department of Informatics at the Luddy School of Informatics, Computing, and Engineering (Luddy). Each of us studies some form of technological mediation— that is, the processes through which subjects, objects, and meanings emerge in interactions between human beings and their social and technical milieu. Members of the center take up a diverse range of project topics, including brain-interfacing technology regulation, how logistical technologies mediate poultry supply chains, the way student-teacher interactions are shaped by online learning platforms, and the technopolitics of large scale, transnational infrastructure projects. What unites us is a common theoretical framework that takes the relations between all entities as our primary unit of analysis.